There are many instances in the bible where people were underestimated. Take David for instance. When God told Samuel to look for a king, David was the last one brought in to be chosen among his brothers as the future king. But look at God. God had already chosen David before man did. So it doesn't matter if people overlook you or count you out. What matters is what God said He would do and the reason He put you on this earth. In other words, whatever God has for you to do, will get done. So there's zero reason to worry about people who tried to stop you, who are trying to stop you, or who will try to stop you.
The writing is obvious. God never underestimates us. And that my dear friends, is what is most important.